InnovAtlasMalaria No More
Research institution

Oregon Health & Science University (OHSU)

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OHSU researchers are developing malaria vaccines, oral and injectable long-acting antimalarial drugs, and other approaches to prevent infection, including compounds that could be used for long-term protection or incorporated into mosquito bednets.

5
Endemic countries
1
U.S. states
4
Products and programs
About

What they do

OHSU researchers are developing malaria vaccines, oral and injectable long-acting antimalarial drugs, and other approaches to prevent infection, including compounds that could be used for long-term protection or incorporated into mosquito bednets.1 They also study malaria prevention in pregnancy and childhood.1 Their U.S. R&D is based in Portland and Beaverton, Oregon, and the work spans the discovery, optimization and development stages.1

In the United States
Products and programs

In the field and in development

Universal malaria T cell vaccine based on HLA-E presentation and multi-stage antibody-based vaccines2,1

Wilder Lab

Endochin-Like Quinolone (ELQ) antimalarials, including long-acting injectable MMV055 (also referred to as ELQ-300)3,1

Riscoe Lab

Next-generation ELQ for oral and injectable prophylaxis against liver-stage malaria infection1

Riscoe Lab, OHSU/Portland VA Medical Center with the WRAIR Division of Experimental Therapeutics

Malaria prevention in pregnancy and children, including clinical studies of malaria chemoprevention and operational/effectiveness research1

Roh Lab

Where they work

Partnerships in 5 endemic countries

Surveillance and genomicsResearchClinical trialsProduct testingPrograms and delivery
  • Institut de Recherche en Sciences de la Santé (IRSS) · clinical studies of seasonal malaria chemoprevention (SMC)1
Kenya
Africa
  • Kenya Medical Research Institute / KEMRI-Wellcome Trust Research Programme (Kilifi) · malaria research collaboration1
Peru
Latin America
  • U.S. Naval Medical Research Unit SOUTH · field-based malaria surveillance and laboratory-based nonhuman-primate research1
Senegal
Africa
  • Université Iba Der Thiam de Thiès (UIDT) · malaria chemoprevention trials1
Uganda
Africa
  • Infectious Disease Research Collaboration (IDRC) · clinical trials evaluating malaria chemoprevention regimens during pregnancy (IPTp)1
U.S. partners

Who they work with in the United States

Sources

Where this comes from

  1. 1Confirmed by the organization
  2. 2mesamalaria.org
  3. 3mmv.org